Oral manifestations in Crohn's disease
Two patient cases from the clinic
DOI:
https://doi.org/10.61872/sdj-2024-06-02PMID:
38739775Keywords:
Morbus Crohn, orale Manifestation, granulomatöse Entzündung, topische SteroideAbstract
Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal system. It is suspected to be caused by a combination of genetic and environmental factors and changes in the patient’s intestinal microbiome. As opposed to colitis ulcerosa, which usually only affects the large intestine, CD may affect various parts of the gastrointestinal tract. Many patients show oral lesions related to CD, which sometimes can precede the first gastrointestinal symptoms. Specific oral lesions include granulomatous cheilitis, cobblestone-like mucosal tags and linear ulcerations. Non-specific lesions occur in the form of angular cheilitis and opportunistic candidiasis, aphthous ulcerations, reduced salivation, dental caries and many more. We present two cases of patients suffering from Crohn’s disease with different oral manifestations and discuss the dentist’s role in early detection of specific oral lesions and the importance of the follow-up care of affected patients.
References
Albert J G, Kotsch J, Köstler W, Behl S, Kaltz B, Bokemeyer B, Fleig W E: Course of Crohn's disease prior to establish-ment of the diagnosis. Z Gastroenterol, 46(2), 187-192. (2008)
Bornstein M M, Baumhoer D, Navarini A A: Das Melkersson-Rosenthal-Syndrom – eine diagnostisch-therapeutische Herausforderung in der Oralmedizin. Swiss Dent J, 133(4), 238-239. (2023)
Cosnes J, Gower-Rousseau C, Seksik P, Cortot A: Epidemiology and natural history of inflammatory bowel diseases. Gastroenterology, 140(6), 1785-1794. (2011)
Feld L, Glick L R, Cifu A S: Diagnosis and Management of Crohn Disease. JAMA, 321(18), 1822-1823. (2019)
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B: Oral pathology in inflammatory bowel disease. World J Gastroenterol, 22(25), 5655-5667. (2016)
Preiss J C, Bokemeyer B, Buhr H J, Dignass A, Häuser W, Hartmann F: [Updated German clinical practice guideline on "Diagnosis and treatment of Crohn's disease" 2014]. Z Gastroenterol, 52(12), 1431-1484. (2014)
Roda G, Chien Ng S, Kotze P G, Argollo M, Panaccione R, Spinelli A, Danese S: Crohn's disease. Nat Rev Dis Primers, 6(1), 22. (2020)
Sahin T, Brygo A, Delaporte E, Ferri J: Die oralen Auswirkungen von Morbus Crohn. Swiss Dent J, 127(7-8), 644-653. (2017)
Schoepfer A, Safroneeva E: [Epidemiology and socio-economic aspects of chronic inflammatory bowel diseases in Switzerland]. Ther Umsch, 75(5), 255-259. (2019)
Tan C X, Brand H S, de Boer N K, Forouzanfar T: Gastrointestinal diseases and their oro-dental manifestations: Part 1: Crohn's disease. Br Dent J, 221(12), 794-799. (2016)
Torres J, Mehandru S, Colombel J F, Peyrin-Biroulet L: Crohn's disease. Lancet, 389(10080), 1741-1755. (2017)
Veauthier B, Hornecker J R: Crohn's Disease: Diagnosis and Management. Am Fam Physician, 98(11), 661-669. (2018)
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 SWISS DENTAL JOURNAL SSO – Science and Clinical Topics
This work is licensed under a Creative Commons Attribution 4.0 International License.
